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EQ-5D-Y [11] was used as a general instrument for HRQOL.
HSCL-25 is a general instrument measuring symptoms of anxiety and depression.
Unfortunately we only used a general instrument and this might be considered as a limitation.
The tool is a general instrument that has its strength in the range of databases covered.
Fatigue, measured by patient self-report or a general instrument (eg, Functional Assessment of Chronic Illness Therapy (FACIT)).
It should be acknowledged, however, that a general instrument such as QHES might have shortcomings for the assessment of cost-effectiveness analyses (Appendix).
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To evaluate the process, a quality assessment instrument (Supplementary Material A) was developed, based on a more general instrument for evaluating the quality of consensus guidelines.
The aim of the present study was to evaluate the psychometric properties of a brief general instrument developed to assess HRQOL.
In future studies it is advisable to use an RB-specific instrument or a vision-related HRQoL instrument besides a general HRQoL instrument.
HRQoL measured by a generic instrument with general public's preference scores can be easily converted to a preference index for use in cost-effectiveness evaluation of healthcare interventions [ 13].
This is a well-known general instrument for measuring the health-related quality of life that is available both in Farsi (the Iranian language) and Swedish [ 11, 12].
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