The phrase "a general hallmark of" is correct and usable in written English.
It can be used to describe a characteristic or feature that is commonly associated with something.
Example: "The ability to adapt to changing circumstances is a general hallmark of successful leaders."
Alternatives: "a typical sign of" or "a common feature of".
A general hallmark of vagueness is that it involves borderline cases: possible cases that are neither clearly in the extension of the vague term nor clearly not in its extension.
Moreover, alteration in normal growth factor responsiveness is a general hallmark of tumorigenesis in numerous cell types.
Age-related decline in immune function, or immunosenescence, appears to be a general hallmark of aging in multicellular organisms.
Angiogenesis is a general hallmark of cancer; therefore, the inhibition of tumor-derived angiogenesis is considered to be an attractive target in the development of anti-cancer agents.
The concept of paternal pronuclear demethylation as a general hallmark of early mammalian development was challenged by reports stating that this process is lacking in rabbit, ovine and pig zygotes [ 15, 19- 21].
Hospitalization was not a general hallmark of clinical severity, as the clinical management of patients changed during the study period, in compliance with the modifications in the National policy of pandemic influenza management.
As mammalian cancer cell lines exhibit a wider range of circadian periods when assessed in vitro than do primary cells, we wonder whether altered circadian timekeeping might constitute a more general hallmark of cells that have lost tumor suppressor genes such as WEE1.
Another general hallmark of epistasis or dominance (intralocus epistasis) is the observation of QTL effects in one but not both backcrosses.
Another general hallmark of viruses is that they can compensate for their small proteomes by the ability to interact with numerous cellular proteins.
Moreover, the recA, uvrA and uvrB genes of N. gonorrhoeae are known to lack the characteristic lexA-binding site or SOS boxes, the general hallmarks of an active SOS response.
