Exact(1)
In summary this population-based study shows COPD is associated with an increased incidence of invasive bacterial infections compared to the general population, indicating a general frailty of acquiring severe infections in addition to the specific susceptibility to infections of respiratory origin.
Similar(59)
B-cell immune frailty is also a marker of general frailty.
The findings of reduced handgrip strength and static balance in the vertebral fracture group may support a relationship with general frailty.
The third possibility is that inability to cope and ill health may have a common origin, such as a genetic predisposition toward general frailty.
The differences in the values reflect the degree of correlation of the variable with either factor, for example; the variable 'angina' has a factor loading of 0.550 on the general (frailty) factor and a loading of 0.619 on its specific factor (Cardiovascular symptoms/disease) with both factors independent of each other.
In general, frailty is understood as an increased vulnerability to a range of adverse outcomes, including death, institutionalisation and worse health [22].
Sleepiness may alternatively act as a marker of an underlying causative factor such as comorbidity or general frailty.
The cost of a patient aged 100 years on RRT is likely to differ from the cost of treating a patient aged 75 years because of general frailty and co-morbidity.
In general, frailty has been defined as "a state of reduced physiologic reserve associated with increased susceptibility to disability". 2 While criteria are being developed to stratify frailty, 3 in this paper we define frailty as patients with severe medical disability- residents of geriatric centers or patients with end stage medical disease.
Although the majority (66.1%) targeted caregivers of patients with Alzheimer's disease or dementia, care recipients had a diverse set of conditions, including cancer (11.6%), general frailty, multi-morbidity or disability (7.4%), post-stroke (4.1%), and other conditions (10.8%).
For example, the general frailty model assumes that the counting process is a non-homogeneous Poisson process given the frailty and covariates, where the frailty is not restricted to follow a gamma distribution [ 33].
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