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Mutations can change the amino acids that a gene codes for, and hence the nature of the coded protein, or they can change the way that transcription factors do (or don't) bind to a given regulatory region.
Biologists usually say that a gene "codes for" a protein, by which they mean that the gene's DNA sequence instructs a cell to build a specific kind of protein; a slightly different DNA sequence might yield a slightly different protein.
Each subset of a DNA chain, called a gene, codes for the construction of a specific protein out of a chain of amino acids.
If a gene codes for several isoforms, the predictions were done independently for each isoform.
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MBs were designed to recognize a 19-bp region of the uid A gene, coding for an enzyme β-glucuronidase.
Imagine that a new advantageous mutation occurs on Chromosome 4, right next to, say, a gene coding for bushy eyebrows and a gene coding for black hair.
However, in the green spotted puffer (Tetraodon nigroviridis), a gene coding for ezh1 could be identified (ENSTNIG00000011694) while ezh2 seems to be absent.
Such an expression manner was distinguished from that of a gene coding for A-type cyclin (Ntcyc 25), indicating that NtEPb genes are not under cell cycle control.
Microarray analysis revealed that GIMAP5, a gene coding for an anti-apoptotic intracellular protein, is upregulated by Notch in T-ALL cell lines.
Studies presented herein indicate that enterocyte targeting with a gene coding for a short antisense against iron transport blocks enterocyte iron uptake, which may have therapeutic value.
Molecular characterization of TRP1, a gene coding for tryptophan synthetase in the basidiomycete Coprinus cinereus.
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