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Cx43 is a gap junction protein, and 18α-GA is the gap-junction inhibitor widely used to inhibit gap junctional communication that is likely to enter cells and modify protein kinases that regulate Cx43 [ 32].
b A gap junction.
Carbenoxolone (CBX) is a gap junction blocker with anticonvulsant properties.
We consider the case of two identical cells coupled by a gap junction.
Cx40 is a gap junction protein important for cell-cell communication in the endothelium.
Cx40 encodes a gap junction protein and is expressed in endothelial cells of large vessels.
Connexins are proteins that oligomerize to form a gap junction channel.
Figure 6a, b shows a gap junction before and after the two-step welding procedure which was performed.
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Stage I waves also have a Gap junction-mediated component refractory to pharmacologic cholinergic perturbation [9] and in addition, it has been observed that intraocular injection of epibatidine perturbs but does not block cholinergic-driven waves completely [20].
In contrast, in cells co-expressing Arf6Q67L a gap junction-like cell cell interface typically remained only in small regions (indicated by arrows in Fig. 5d).
During the first postnatal days, the synchronized oscillatory activity of the mouse cerebral cortex is driven by subplate activity and spreads through a gap junction-coupled neuronal network (Dupont et al. 2006).
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