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These experiments suggest that calcium affects the ERK5 cascade either at the MAP3K or at a further upstream level.
The 3′ region polymorphisms do not affect VDR protein structure, while Fok 1 (C T transition) alters an ACG codon resulting in a further upstream start codon and a three amino-acid extended protein (Saijo et al, 1991).
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Structural analysis showed that parts of the ironwork were overloaded, and so in 1981 a new concrete aqueduct was cast by John Laing Construction Ltd, on a site a little further upstream.
In 1930 a new bridge was built nearby, a little further upstream, and as part of the work, the fifth arch was removed and the bridge was returned to its Medieval width.
4. Swim in the Danube The Exit festival campsite has its own beach, but you may want to take in a bit of local colour at the "Strand" lido, situated a little further upstream on the north bank.
A new study reported in this issue of EHP implicates a gene further upstream of previously demonstrated mechanisms.
The joy of this kind of joke is the way a hand is stretched out across the footlights from the period play to the present day: just for a moment we are all in the same glorious boat, pushed a little further upstream than the normal tides allow, before it changes and we are back again in the world of the play.
A little further upstream, the dead and dying fish were packed so closely together you could almost walk on them.
Initial reports at the start of the year suggested a crossing between Tilbury and Gravesend, replacing a ferry service, but this had been rejected by July in favour of a route further upstream, near Dartford.
This moves the question of how paclitaxel kills breast cancer cells a step further upstream from the mitochondrion.
In the remaining 33 cases the RACE sequence(s) RACE data imply a TSS further upstream than the EST sequence in 21 of those 33 ORs, but for the other 12, EST sequences extend further upstream.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com