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The phrase "a further significant" is correct and usable in written English.
It can be used when you want to emphasize an additional important point or detail in a discussion or argument.
Example: "The study revealed a further significant correlation between diet and mental health."
Alternatives: "an additional important" or "a more substantial".
Exact(60)
Later still, he let slip a further significant detail.
A further significant enhancement (delta band) was identified in the right temporal lobe (Fig. 2C).
The World Bank recorded a further significant 25% drop to 3.3% in the decade and a half to 2009.
Rock mass strength seems to have a further significant effect on these relationships.
(A further significant eruption in 2003 destroyed additional land then under cultivation).
With optimisation of the process, a further significant increase in deposition rate can be expected.
Negotiations on the details of the agreement, including a further significant easing of Israel's blockade of Gaza, are continuing in Cairo, Egypt.
Freddie George at Seymour Pierce said: Q1 figures to the end of May show another disappointing result from Argos, which saw a further significant decline in electrical sales.
But he adds: "In practice, the political momentum behind the programme is so strong that a further significant postponement does not appear likely".
A further significant finding by the Francis inquiry was the clear link between the drive to achieving foundation trust status and a subordination of clinical concerns.
We considered it as something quite new, about which there were many discussions". Later still, he let slip a further significant detail.
More suggestions(18)
a further prominent
a further sensitive
a further abundant
a further remarkable
a further sizeable
a subsequent significant
a further notable
a greater significant
a greatly significant
a further noticeable
a further significance
a further distinctive
a further major
a further considerable
a further useful
a further landmark
a furthermore significant
a future significant
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com