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A key characteristic of p53 tumours was the presence of a major protein protein interaction hub composed of several proteins involved in cytoskeletal organisation (Actn1, Actn4, Sept7, Sept 9 and Plec), as well as a further hub centred on Itgb1.
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Further hub loci are PTPN22, a known player across several autoimmunity disorders [ 17], and IL23R, which has been shown to direct inflammatory processes [ 18].
Another aspect of integrating logistics hubs into modelling is the inclusion of further hub characteristics that excess the characteristics mentioned above (capability of handling certain shipments).
Beside a general integration of hubs, the differentiation of diverse types of transport logistics hubs represents a further step in considering and distinguishing hubs in demand modelling – also with regard to node-specific characteristics within a category [11, 13].
Each turbine begins 30 metres beneath the seabed, rises through about 20 metres of water, with the turbine hub a further 80 metres above the surface.
On location: Situated on one of Cambridge's main thoroughfares, at 10 minutes' walk from the railway station and a further five from the central hub of shops and colleges, the stylish, split-level Picturehouse literally occupies the cultural high ground, its upper floors overlooking a row of Wagamamas, estate agents and All Bar Ones.
Rason has also become the first place in North Korea where you are allowed to own your home.The government has announced a further 19 SEZs since 2013, small hubs of between two and four square kilometres for everything from tourism (Chinese occasionally holiday in the North) and software development, to fertiliser- and rice-production.
A further $1.5 billion will come from other Middle East investors after Xojet establishes a hub in Abu Dhabi, Touw said.
A further analysis on this subset revealed that besides the two UBQ10 hubs, two other transcription factors closest to AS1 (Cit.42831.S1_and and MYB16 (Cit.19398.1.serve) serve as smaller hubs linking the larger UBQ10 hubs.
Further, the hub genes of the B-cell C3NET gene regulatory network were identified to play crucial roles in cell signaling, adhesion and cell proliferation processes.
When Obama announced a "website that will serve as a hub for further transparency," I really didn't expect a Tumblr http://t.co/DgXCWCiG0O — joshuafoust (@joshuafoust) August 21, 2013 The contents of the releases themselves, including official statements, video and testimony, were no different from what the office released on its own Web site, which raises the question: why make a Tumblr?
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