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Using the curved lattice structure described here as a model for fitting the atomic structure of the NEC heterodimer (Zeev-Ben-Mordehai et al., 2015), we have defined exact interaction surfaces that could be used as a further constraint for structural and functional homology modeling of putative cellular counterparts.
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We add a further constraint that, for each pair of TFs, at least one annotated binding site pair is within a cluster, i.e., sufficiently close to each other, as is typically the case in real promoters as well [76].
The available amount of substrates is a further constraint which is implemented as a hard constraint for the input variables.
After the pairings for one round had been solved, we added a further constraint to prevent the same pairs being selected again in future rounds.
They add that political considerations are a further constraint.
A further constraint, such as a rate ratio, is needed.
A further constraint is that the fusion gene must keep a certain length.
As a further constraint, we only considered repeat copies with a minimum length of 50 bp.
This may represent a further constraint on putting the ideal of professional interpretation into practice.
A further constraint in improving global nutrition is the lack of capacity in nutrition science.
Applying one further constraint for acetate production resulted in a predicted growth rate of 0.095 hr-1.
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CEO of Professional Science Editing for Scientists @ prosciediting.com