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A further confounding factor which may have affected outcome was time from injury to surgery.
In the orbit, the high metabolic activity of extraocular muscles acts as a further confounding factor [69].
These effects all suggest that glucose regulation is affected by isoflurane, which is a further confounding factor in studies involving isoflurane.
A further confounding factor might be that patients and witnesses might miss the headache because they are overwhelmed by the dramatic manifestation of a seizure.
The lower SNR in estimating the fast diffusion component reduces the diagnostic value of such parameters and a further confounding factor arises from the impossibility to reach the desired low diffusion-weighting because of limitations of the scanner hardware [26].
A strong variability was observed in the blood glucose levels of the anaesthetised rats between scans, and from before to after the scan, which suggests that this could be a further confounding factor of isoflurane on FDG studies.
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Sensitivity analysis for the assumed distribution of an individual potential confounder, as reported in this article, is inadequate to account for the potential effects of such a long list of known confounders and can make no allowance for any further confounding factors of which we are unaware.
One further confounding factor is suggested by the significantly increased total IgE seen in FSHS patients vs. nSHS patients.
Further confounding factors arise as recent studies have revealed the presence of the C-epimer form of 25OHD3 in adult blood samples [11], which was subsequently quantified in further studies [3, 12, 13].
However, we acknowledge that there may have been further confounding factors we could not take into account.
Further confounding factors are technical differences like the platforms used (RNAseq or different microarrays) and the tissue types used to identify enriched or selective expression.
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