The phrase "a fundamental restriction" is correct and usable in written English.
It can be used when discussing a basic or essential limitation or constraint in a particular context, such as rules, regulations, or conditions.
Example: "The new policy imposes a fundamental restriction on the use of company resources, ensuring they are allocated efficiently."
Alternatives: "a basic limitation" or "an essential constraint."
OrthoMCL family size can be adjusted by changing the inflation index (1.5 in this study), but this does not loosen the fundamental restriction that the algorithm begins with a list of putative orthologs and paralogs.
But the fundamental restriction remains the properties of the television itself, particularly now that digital cameras are able to harvest far more color information than goes out over the air.
In this paper, I develop a rich set of design limits that describe fundamental restrictions on how a policymaker can alter variance at different frequencies.
Rather, he argued, that "no matter what the state of A+S is, there is in principle a complete set of commuting operators for which it is an eigenstate, so that, at least, the determination of these quantities will not affect the state nor in any way disrupt the operation of A," nor, he added, are there "fundamental restrictions in the usual theory about the knowability of any state functions".
It was frequently difficult, in considering comments, to determine whether a doctor's criticisms related primarily to the fundamental restrictions of working hours imposed by the EWTD itself, or whether it was the particular manner of implementation in a particular country, hospital Trust or unit which was at fault.
The more fundamental restrictions, however, are cultural rather than political.
The proposal would loosen one of the most fundamental restrictions on the conduct of the Federal Bureau of Investigation and would be another step by the Bush administration to modify civil-liberties protections as a means of defending the country against terrorists, the senior officials said.
Thus, because of this simplicity and symmetry of the suspension geometry and of the PTO mechanism, the fundamental restrictions of other linear, pendulum or gyroscopic variants on inertial reacting bodies are significantly removed.
And because we get lots of links (and there aren't fundamental restrictions on copying the web pages) we get innovative companies like Google that index the links and rank web pages, higher or lower, based on the number of links referring to those pages [10].
These fundamental restrictions that are intrinsic to comparative and target analysis are not easily circumvented and they necessitate an independent, spectroscopic "bottom-up" approach to the molecular-resolution characterisation of these complex unknowns.
