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The phrase 'a fundamental problem of' is correct and usable in written English.
You can use it when you are introducing a problem that is an essential or central element of an issue. For example: "A fundamental problem of this project is that there is not enough financial support."
Exact(54)
This is a fundamental problem of publicly traded private equity firms.
Because the problem with the markets isn't just a lack of liquidity — there's also a fundamental problem of solvency.
So there's a fundamental problem of a huge shortfall of the resources available to countries in the developing world.
He said: "It's too early to tell whether it's a game-changer, but it is addressing a fundamental problem of addressing shrinking reach in the core markets".
The picture of Dr. Bernard Kaminetsky's waiting room showing snacks of cake and bagels captures a fundamental problem of medical care, including concierge doctors: inadequate attention to prevention.
Cable said: "We have a fundamental problem of excessive profits in the banking system which has got be dealt with through structural reforms.
Similar(5)
Although inadequate funding for health is a fundamental problem, inefficient use of resources is of great concern.
But there's a fundamental problem: a copy of you will only ever be a copy of you, even if it has your personality and all of your memories.
A fundamental problem in analysis of highly multivariate spectral or chromatographic data is the reduction of dimensionality.
Their ridiculous behavior is born of a fundamental problem: their basic philosophy of borrow and spend, and tax cuts for the upper 1% of the population, has failed, and spectacularly so.
The meetings were revived in 2008, but Mr. Craner said that China's diminishing regard for the United States remained a fundamental problem undermining discussions of this nature.
More suggestions(16)
a fundamental shortcoming of
a fundamental issue of
a central problem of
a significant problem of
a major problem of
a fundamental subject of
a main problem of
a crucial problem of
a fundamental challenge of
a critical problem of
a core problem of
a fundamental principle of
a fundamental component of
a fundamental part of
a fundamental difference of
a fundamental tool of
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com