Sentence examples for a fundamental precursor from inspiring English sources

Excess adiposity is a key risk factor for congestive heart failure (CHF) (1) and cardiovascular disease (CVD) (2), in part because it is a fundamental precursor of several vascular risk factors including high blood pressure, dyslipidemia, and impaired glucose homeostasis.

A robust high-density genetic linkage map for P. maxima is a fundamental precursor to understanding the architecture and evolution of pearl oyster genomes, determining the genetic basis of complex phenotypic traits under natural and industrial settings, and identifying genes and quantitative trait loci (QTL) associated with bivalve shell biomineralization.

"While the historic summit between the North and the South holds the promise of reconciliation and change, no evidence exists of the fundamental precursors for change," said the report, which has not made public.

Respect and reciprocity were also viewed as fundamental precursors to enabling patients to be honest about their ability and desire to self-manage, deemed essential by the PACCTS study authors, for planning sustainable behaviour change beyond the duration of a trial.

NRG1/ErbB signaling plays a fundamental role in SC precursor growth and in interactions between SC (expressing ErbB2-ErbB3 and soluble type I/II NRG1) and axons (mainly expressing transmembrane NRG1-type III). NRG1-type III

High-throughput transcriptomic profiling approaches have revealed that alternative splicing (AS) of precursor mRNAs, a fundamental process by which cells expand their transcriptomic diversity, is particularly widespread in the nervous system.

Among these, the histone methyltransferase EZH2 is a fundamental negative regulator of myogenic precursor differentiation by repressing the expression of myogenic genes through the H3K27me3 mark deposition on the promoters of myogenic genes [ 22, 28].

EPCs are the precursors of endothelial cells and play a fundamental role in the maintenance of endothelial integrity and function by both developing into endothelial cells and secreting vasoactive substances [ 29, 30].

Even though the pathogenesis of myelodysplastic syndromes (MDS) is dominated by specific molecular defects involving hematopoietic precursors, also immune mechanisms seem to play a fundamental functional role.

Eicosapentaenoic acid (EPA) is the precursor for eicosanoids and the docosahexaenoic acid (DHA) is a fundamental structural component of grey matter and retina.

A fundamental question in biology is how multicellular organisms can arise from their single-celled precursors.