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Discover LudwigThe phrase "a fundamental issue of" is correct and usable in written English.
It can be used when discussing a core or essential problem related to a particular topic or subject matter.
Example: "The debate surrounding climate change is a fundamental issue of our time that requires immediate attention."
Alternatives: "a core concern regarding" or "a key matter of".
Exact(47)
There is a fundamental issue of business compatibility.
There is a fundamental issue of trust here.
This paper addresses a fundamental issue of component manufacture.
For me it it's a fundamental issue of how God meant things to be.
Smaller businesses say there is also a fundamental issue of fairness.
Design seismic motion represents a fundamental issue of many geotechnical applications.
Similar(13)
Similarly, language rights are a fundamental issue for the millions of Kurds in Turkey.
We don't think it is a fundamental issue, more of a translation issue".
All those factors were directly or indirectly associated with a fundamental issue: mismapping of NGS reads to a reference sequence.
Chuck Hagel gave his first major policy address as secretary of defense and devoted a good amount of space to a fundamental issue: the parameters of conventional military power.
This is a fundamental issue in need of clarification, as spatiotemporal control of RNA deposition, expression, and turnover are central to proper ontogenesis [ 17- 19].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com