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In the lipid metabolism cascade, addition of coenzyme A (CoA) to fatty acids is a fundamental initial step in the utilization of fatty acids for structural and storage lipid biosynthesis, signaling lipid protein acylation, and other metabolic processes [ 8].
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Acyl-CoA synthetases (ACSs) are the key enzymes responsible for this fundamental initial step in lipid metabolism.
Quantifying the differentially expressed miRNAs in the different tissues is an important initial step to investigate the fundamental functions of these miRNAs.
Expressing your concern is always a great initial step.
And the CEA would be a big initial step in that direction.
It is a very initial step to tackle this problem.
Critics note that, as in other new democracies, an election is only an initial step.
Establishing regional DHS offices would be an important initial step.
While increasing knowledge may be an important initial step, whether knowledge alone can directly translate to changes in behaviours remains questionable [ 16], which is why efforts to increase students' self-efficacy is a fundamental part in personal change, as it motivates people to act [ 17].
It is in such environments where an initial step of noise filtering and reduction of data set size plays a fundamental role.
As an initial step to put this framework into operation, we propose using a matrix formulation to move both backward toward the more fundamental causes of disease, and forward toward disease burden.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com