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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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a fundamental difference of

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "a fundamental difference of" is correct and usable in written English.
It can be used to highlight a significant distinction or variation between two or more concepts, ideas, or entities. Example: "There is a fundamental difference of opinion between the two experts regarding the best approach to climate change."

✓ Grammatically correct

Science

News & Media

Formal & Business

Human-verified examples from authoritative sources

Exact Expressions

21 human-written examples

This means most of the 66 miRNA clusters are composed of the miRNAs from either one family or completely different families, suggesting that there is a fundamental difference of family composition between the homo-clusters and the hetero-clusters.

It's a fundamental difference of opinion.

News & Media

The New York Times

There's a fundamental difference of opinion here, folks.

News & Media

The New York Times

The Hollywood star then cut ties with the charity, citing "a fundamental difference of opinion".

At issue is a fundamental difference of belief over the source of the conflict.

News & Media

The New York Times

"She and Oxfam have a fundamental difference of opinion in regards to the boycott, divestment and sanctions movement.

News & Media

The Guardian
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Human-verified similar examples from authoritative sources

Similar Expressions

39 human-written examples

However, together we can make a fundamental difference for millions of children in the Horn of Africa".

Formal & Business

Unicef

Differences in the underlying data result, at this point, in a fundamental difference to the approach of Lappi (1997) and Mehtätalo (2004).

But if we want to make a fundamental difference, all of us must bring the conversation home.

Bank cards and lines of credit both offer money when it is needed, but there is a fundamental difference: lines of credit have low, fixed interest rates or slow-moving, variable ones, while interest rates on credit cards can jump unpredictably.

News & Media

The New York Times

However, the commonalities between GBM and non-GBM with respect to race/ethnic group and sex variation, more notable than the somewhat subtle, albeit statistically significant, differences, suggest that within the context of a fundamental difference, some aspects of the complex process of gliomagenesis are shared by these subtypes as well.

Science

BMC Cancer
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Expert writing Tips

Best practice

When using "a fundamental difference of", ensure you clearly articulate what two or more things are being compared and what specific aspect constitutes the difference. This avoids ambiguity and strengthens your argument.

Common error

Avoid using "a fundamental difference of" when the distinction is minor or superficial. Overusing the phrase can dilute its impact and make your writing seem exaggerated. Instead, reserve it for truly significant and impactful differences.

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

83%

Authority and reliability

4.5/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "a fundamental difference of" functions primarily as a noun phrase, often acting as a subject complement or object of a preposition. It serves to identify and emphasize a significant distinction between two or more entities, ideas, or viewpoints. Ludwig indicates that it is grammatically correct.

Expression frequency: Common

Frequent in

Science

30%

News & Media

52%

Formal & Business

9%

Less common in

Encyclopedias

2%

Wiki

3%

Reference

4%

Ludwig's WRAP-UP

In summary, "a fundamental difference of" is a grammatically sound and frequently employed phrase used to emphasize a significant distinction. As Ludwig explains, its primary function is to highlight core variances across various contexts, from science and news to formal business settings. While alternatives like "a key disparity of" or "a significant divergence of" exist, "a fundamental difference of" remains a strong and versatile choice. Remember to reserve it for truly impactful differences to maintain its effectiveness, as overusing it can dilute its significance.

FAQs

How do you use "a fundamental difference of" in a sentence?

Use "a fundamental difference of" to highlight a significant distinction between two or more things. For instance, "There's a fundamental difference of opinion between the scientists regarding the safety of the new drug".

What's a more formal way to say "a fundamental difference of"?

For a more formal tone, you can use phrases like "a key disparity of", "a significant divergence of", or "a principal dissimilarity of". See more at "a principal dissimilarity of".

Which is correct: "a fundamental difference of opinion" or "a fundamental difference in opinion"?

Both "a fundamental difference of opinion" and "a fundamental difference in opinion" are acceptable. The choice often depends on stylistic preference, though "a fundamental difference of opinion" is slightly more common, especially in certain contexts.

What can I say instead of "a fundamental difference of" to emphasize a contrast?

To emphasize contrast, consider using phrases such as "a radical contrast of" or "a marked contrast of". These alternatives highlight the opposing nature of the difference. See more at "a marked contrast of".

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Source & Trust

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Authority and reliability

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Expert rating

Real-world application tested

Most frequent sentences: