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The phrase "a fundamental concern when" is correct and usable in written English.
It can be used to introduce a topic or issue that is of primary importance in a specific context or situation.
Example: "Environmental sustainability is a fundamental concern when developing new urban infrastructure."
Alternatives: "a key issue when" or "a primary consideration when".
Exact(3)
Establishing the time at which a particular event happened is a fundamental concern when relating cause and effect in any forensic investigation.
This is a fundamental concern when the donor has parental consanguinity, an increasing factor for autosomal recessive illnesses such as the above-mentioned one.
Accordingly, monitoring of dissolved oxygen (DO) concentration is of particular importance at all scales, and characterization of transfer is a fundamental concern when scaling down to mini and microvolumes.
Similar(57)
Sampling challenges are of fundamental concern when the entire validity of a research study may be questioned depending on the method selected.
UWB technology with joint consideration of directional antennas can benefit when compared to classical omni-directional antennas from the energy conservation viewpoint, which is of fundamental concern when it comes to wireless sensor networks (WSNs).
A fundamental concern of animal communication is when and where to emit signals.
A fundamental concern of ethics is the effect of our actions on others.
Such machines consume oodles of power, so heat dissipation becomes a fundamental concern.
"Now there's a fundamental concern that wasn't there before," said David Scott, who lives in Midtown.
But their objections also have to do with a fundamental concern: liberty is not something one can simply sneak around.
Security is a fundamental concern in modern vehicular systems.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com