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In Denmark, Dr. Rasmussen is seeking to design the most stripped-down minimalist suggestion of a functioning cell.
The first ancestral gene set that potentially could be a realistic candidate for a functioning cell was LUCA0.9.
Thousands of proteins must function together in an integrated manner to use and to produce the many molecules necessary for a functioning cell.
Metabolic pathways consisting of metabolites, biochemical reactions transforming a set of metabolites to others and enzymes catalyzing these reactions provide valuable information regarding material processing centers of a functioning cell and cellular metabolism in general.
Several studies [ 19, 13, 14, 20] have tried to identify essential genes by deriving a minimal set of genes needed to sustain a functioning cell under ideal conditions, normally meaning unlimited amounts of nutrients and no competition from other cells.
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Although Reuter admits that developing a complete computer simulation of a functioning cell--a process that all EML life sciences researchers are already contributing to--is still a good bit away, he sees the long-term fruits of their research to be "of huge relevance to understanding fundamental biology to drug design".
In a properly functioning cell, the ubiquitin tags the oncoproteins for degradation.
We can only claim to understand life, synthetic cell experts argue, if we are able to technically reproduce a fully functioning cell.
Dr. Church expects to have a proof of concept — a functioning mirror cell that serves some useful purpose — in two years.
(B ) Localization of CpoB-mCherry as a function of cell cycle progression (cell length), with comparison to other proteins.
a NP uptake per cell as a function of cell density.
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