Sentence examples for a functional rationale for from inspiring English sources

Given that many of the genes encode products of unknown function, we cannot offer a functional rationale for these observations other than to suggest caution when interpreting expression changes for these genes in responses of cells with the Δ pyrF genotype.

We looked in the acoustics for a functional rationale for the frequency-dependence of neural tuning to ITD within single neurons.

In some cases there may well be a functional rationale for such redundancy (it is common to find genes for both class Ia and Ib in bacterial genomes), but in the absence of direct evidence for subfunctionalisation and selection on subclass paralogues, the null hypothesis should be that this represents functional redundancy.

This functional rationale is suitable for the pregnancy period because the dynamic physiologic changes on the erythrocyte indices and biomarkers of iron metabolism [ 30- 34].

However, the validation of their program is not enough for providing functional rationale to support their concept.

6) Identifying previously unrecognized members of the fold, if any, and thereby expanding the functional spectrum or providing a rationale for function prediction of uncharacterized members of the fold.

These expression data provide a strong rationale for the functional analysis of Tβ10 in CCA.

Although statistical methods can provide a prediction of the likely driver and passenger mutations within a cancer, there is a strong rationale for using functional assays to test these predictions.

These findings provide a strong rationale for using functional approaches to contribute additional data to support multifactorial predictions, with the caveat that such approaches are most useful for assessment of variants located in known functional domains for which in vitro functional assays have been developed.

Clinical RS and its unfortunate functional consequences for cancer patients also provide a rationale for a predictive assay for testing for Rad21 status prior to RT, as a form of molecularly individualized medicine.

Functional studies that can provide a biological rationale for our observed associations would be useful in recommending molecularly targeted therapies.