In two previous trials of solanezumab, called EXPEDITION and EXPEDITION II, Lilly used both a cognitive test and a functional measurement to track the response of people with both mild and moderate Alzheimer's disease.
Without complexities of sample preparation and potential toxicity of exogenous biomarkers, autofluorescence imaging of endogenous fluorophores promises a noninvasive method for functional measurement of the retina [ 13].
This is due to the fact that averaging the functional measurement of a system over many trials helps to reduce the noise existing inside the system and, thus, helps to represent the dynamical process in the system more precisely [ 31].
Continuous EEG-SEP monitoring is a relatively new, noninvasive bedside monitoring tool that allows functional measurement of neurological impairment.
Functional measurement of knee joint position sense after anterior cruciate ligament reconstruction.
In the resulting engineered cells, isolated functional measurement of the remaining allele carrying the rare mutation of interest is possible.
The sample substrates were prepared for modeling the case of the functional measurement of the brain or retina.
In this cohort, expression of three of these miRNAs (miR-149, miR-133a and miR-133b) correlated with functional measurement of emphysema severity (KCO, Figure 1).
However, as IL-1β presents plentiful effects on cartilage, the functional measurement of IL-1β on GAG-precursor synthesis would further strengthen the evidence in the present study.
