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Given the sequence and predicted structural similarities between periostin's cassette exons due to the underlying repeat structure laid out in this study, we detail below a functional interpretation that employs a dose-type rationale, i.e. a binding interaction as a function effectively tuned by exon count.
The agranular architecture of motor cortex lacks a functional interpretation.
A functional interpretation of the role of the N-terminus of ERK1 is that it segregates the catalytic action of ERK1 to cytoplasmic targets.
Recent detailed study of Macroleter has suggested a close relationship to the large pareiasaurs [18]; however, neither a comprehensive phylogenetic treatment considering all the relevant taxa, nor a functional interpretation of the cranial anatomy has been performed to date.
In particular, the necessity for providing a functional interpretation at molecular level that accounts for the genome-scale experimental designs has promoted the development of different methods for the functional analysis of this type of data in the last years [1], [2].
The participants seemed to make use of a functional interpretation of the disorder-criterion.
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This model gives a detailed functional interpretation of the six-layered columnar cortical architecture and related subcortical structures.
However, this interaction would not lead to a straightforward functional interpretation as CpG islands with high CpG density are generally refractive to DNA methylation and a function of Dnmt1 as a de novo DNA methyltransferase is not well established.
Co-expression has been largely used to infer gene regulatory networks [ 61- 63], but these approaches normally ignore the participation of the genes in pathways and hence are limited in providing a global functional interpretation of the results [ 64].
As budding yeast is the only model organism where there is a 1 1 relationship between the cenH3 nucleosome and the microtubule attachment site (Furuyama and Biggins, 2007), any conclusion concerning its composition and structure has an unequivocal functional interpretation.
A more systematic functional interpretation of differentially transcribed genes was obtained through an enrichment analysis using Database for Annotation, Visualization, and Integrated Discovery DAVIDD) software [ 54, 55] considering the GO Biological Process Database.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com