The phrase "a functional interplay between" is correct and usable in written English.
It can be used to describe the interaction or relationship between two or more elements that work together effectively.
Example: "The study highlights a functional interplay between cognitive processes and emotional responses in decision-making."
Alternatives: "an effective interaction between" or "a productive relationship between".
Our data suggest a functional interplay between INO80's Arp8-Arp4-actin and Arp5 modules in sensing the DNA length separating nucleosomes and regulating nucleosome positioning.
Moreover, the discovery of interchromosomal or long-range intrachromosomal interactions in higher eukaryotes points to a functional interplay between genome architecture and gene expression, challenging the view of transcription as a two-dimensional process (Gondor and Ohlsson, 2009; Schoenfelder et al., 2010).
Recently, we have established a functional interplay between TRPV1, a close homologue of TRPV4, and the microtubule cytoskeleton [31] [35].
It was recently found that there exist a functional interplay between alcohol-induced liver damage and TGF-β signaling [24].
This hypothesis is supported by strong linkage disequilibrium between variants in pfcrt and pfmdr1 [23], [23], perhaps involving a functional interplay between these proteins.
Biphasic insulin secretion is triggered by electrical signalling in the beta cell as a result of a functional interplay between KATP channels, KV-channels and voltage-dependent Ca2+ channels [2] [7].
These results demonstrate a function of USP13 in ERAD downstream of retrotranslocation and suggest a potential functional interplay between USP13 and Bag6 that is required to maintain retrotranslocated substrates in a soluble and degradable state.
Our approach led us to discover a novel functional interplay between interphase Cdks and the chromatin association of a variety of novel candidate proteins such as Cdk1 itself, the APC/C regulatory subunit cdc20, the PP4 regulatory subunit Smek2, the helicase FUBP1, and the PHD domain-containing zinc finger protein PHF6.
In addition, we identified a class of mutations affecting chromatin modifiers linked to transcription, consistent with a close functional interplay between condensin and the transcription machinery.
BM endothelial cells are major regulators of haematopoiesis12,13,14,15. Genetic deletion of crucial haematopoietic factors such as the chemokine CXCL12 or stem cell factor (SCF) in endothelium results in partial to almost complete depletion of HSCs from the BM, thus proving a major functional interplay between these cell types16,17,18.
Overall, this genetic screen reinforces the idea of a tight functional interplay between condensin association with chromatin and transcriptional processes.
