The phrase "a functional influence on" is correct and usable in written English.
It can be used to describe the effect or impact that something has in a practical or operational context.
Example: "The new policy has a functional influence on employee productivity and morale."
Alternatives: "a practical impact on" or "a significant effect on".
Histone modifications have long been thought to have a functional influence on the regulation of transcription.
Collectively, these observations suggest that CRC cell-derived microvesicles carry mRNA, together with proteins and lipids, which may exert a functional influence on CRC-related processes.
The low expression of ERBB2 remained unchanged [see additional data file 2], so we further investigated whether LL-37 had a functional influence on ERBB2.
In a recent study performed in SLE, a three-variant haplotype in CD226 gene, comprising CD226 rs763361-rs34794968-rs727088, was found to be associated with SLE and the authors proposed that rs727088 may be the single nucleotide polymorphism (SNP) with a functional influence on CD226 transcription levels [ 23].
In order to elucidate whether the up-regulated MST1 kinase exerts any functional influence on neurogenic muscle atrophy, we examined atrophy process in muscles from three- to five-month-old adult WT and MST1 KO littermate mice.
Therefore for supercoiling to have a structural or functional influence on DNA or chromatin it must operate within a constrained environment where the energy is at least transiently trapped or restricted.
The efferent pathway of the anti-inflammatory vagus nerve reflex is still not fully understood but there are many reports showing a multisynaptically mediated functional influence on spleen lymphocytes involving the alpha7-nicotinic receptor [7].
However, about the biological meaning of such silent binding events can be speculated, but may for instance be explained in part by the interaction of FOXP3 with other transcription factors that may attenuate or block its functional influence on the transcription of an adjacent gene.
Identified eQTLs could then be tested as potential disease-susceptibility candidates in genetic association studies, with the expectation that variants with functional influence on gene expression would have a higher likelihood of influencing clinical traits.
To display the power of this approach, we explored ectopic expression of a Wnt ligand in the mouse intestinal mesenchyme and demonstrate its functional influence on the adjacent epithelium.
Such coupling could incorporate specific inhibitory/excitatory pathways that are well known in these circuits, but whose functional influence on firing in MDN are still not well understood.
