Sentence examples for a functional implication of from inspiring English sources
A functional implication of NOX-inhibitory activity of thioridazine was demonstrated by its ability to block redox-dependent myofibroblast differentiation.
Our results are consistent with previous ones, and further support the idea of a functional implication of the isochores in gene expression.
Time-dependent expression of this mRNA consequently resembles the pattern of DHX58, again suggesting a functional implication of the encoded protein in response to infection.
Such a relationship would provide additional evidence on a functional implication of the isochores, supporting that they are mainly a product of evolutionary adaptation [ 2, 4], rather than a simple by-product of neutral evolutionary processes [ 9- 11].
A functional implication of stable CENP-A occupancy of promoters/DHS and its correlation with transcription factor binding sites is the potential link to gene expression changes reported in cancer cells.
More importantly, they provided evidence for a functional implication of T-type Ca2+ channels in the proteolytic processing of APP where proper channel activity is required for non-amyloidogenic processing of APP, precluding the production of Aβ and possibly associated senile plaques.
A functional implication concerns the role of the IGL as a mediator of circadian system response to tonic light exposure.
It has been reported that activation of the ERK MAPK pathway upon CD95 crosslinking has a functional implication in nerve recovery and prevention of CD95-induced apoptosis.
Upregulation of mir32 in thyroid cancer vs. benign thyroid tumors has been detected in a microarray study; however functional implication of this microRNA in PTC is not known yet [ 50].
Nevertheless, to which extent cell-based assays can predict the functional implication of a given factor within the whole organism remains a debated matter.
To establish a system to analyze the functional implication of BST-2 expressed in cancer cells, we suppressed BST-2 expression in two murine mammary cancer epithelial cell lines, E0771 cells [ 29] and 4T1 cells [ 30].
