The phrase "a functional impact on" is correct and usable in written English.
It can be used when discussing the effects or consequences that something has on a particular function or operation.
Example: "The new software update has a functional impact on the system's performance, improving speed and efficiency."
Alternatives: "a practical effect on" or "a significant influence on".
Syk has several interacting signaling partners e.g. Vav, the phophoinositide-specific phospholipase C PLCC) isozymes PLCγ-1 and PLCγ-2, and Cbl which are known to exert a functional impact on different leukocyte functions including cell migration [10] [17].
Polymorphisms having a functional impact on gene expression can function as markers for more complex processes underlying individual differences in reaction to family adversity, and therefore provide us with clues on possible underlying mechanisms.
Dr. Barr testified that he did not believe that Mr. Jon's intelligence had a "functional impact" on his life.
This first set of data shows that the LDTg is activated by stress, and that its remote chemogenetic inhibition has a functional impact on VTA DA neurons activity.
To examine if lysine to arginine mutagenesis has a functional impact on the ability of TIR1 to recognize mAID, we replaced all lysines present in mAID but not in vhhGFP4 (mAIDK→R-vhhGFP4) (Supplementary Figure 1d).
To investigate whether Gadd45a deletion has a functional impact on the colony-forming capacity of ATM−/− HSCs, we conducted single-cell colony forming assay.
A recent publication demonstrated a functional impact of ITGAM polymorphisms on ex vivo neutrophil functions, independent of R77H [ 44].
We furthermore revealed a functional impact of CTA 157-2 on the proteasome when testing different concentrations of CTA on AMC cleavage from LLVY by 20S proteasome.
In our recently published manuscript in Cell Death Discovery, it was proposed that the cell surface glycosaminoglycan (GAG) chains from CD44 proteoglycans have a relevant functional impact on P2X7-receptor physiology, emerging as a new cofactor that is necessary for the full receptor activity and a new post-translational regulatory mechanism for purinergic signaling at the cellular level.
Finally, to determine if factors that increase personal perceptions of risk had a practical functional impact on HCWs in the full sample, we identified an item in survey A that could serve as a proxy for the survey B factors that mediate vulnerability.
It is important to consider that hyperoxia exposure or other causal factors that drive aberrant lung alveolarization may concomitantly modulate microRNA expression that, while without a direct functional impact on lung development per se, may participate in pathogenic processes related to comorbidities noted in BPD patients.
