Sentence examples for a functional effect on from inspiring English sources

By comparing the prediction scores obtained from all the six in silico tools, 2 nsSNPs at positions ALK F1174L and ALK R1275Q in the coding region were predicted to have a functional effect on protein function and stability.

Interestingly, rs9461045, one of these two markers, has a functional effect on the expression of KIAA0319 (29).

The analysis of the sequences did not evidence new mutations with a functional effect on the development of disease.

Two indigenous bacterial consortia, IMP-100 and IMP-200, proved to have a functional effect on heavy crude oil recovery, indicating a potential implementation in Microbial Enhanced Oil Recovery (MEOR).

To investigate whether this methylation had a functional effect on expression of SFRP3, we used RT-QPCR and immunofluorescence.

Our results demonstrate that mth alleles segregating in nature have a functional effect on all three traits.

The gene regulation results show a functional effect of IFI16 on GR function, and coimmunofluorescence studies show that IFI16 and GR are colocated in both cytoplasmic and nuclear compartments.

Suppression of recombinant HCN2 single-channel activity by KCR1 clearly demonstrated a functional effect of KCR1 on HCN channel behavior.

This suggests that the reduction in mechanical pain sensitivity was due to a functional effect of BoNT‐A on mechanosensitive nociceptors.

This correlates with a functional effect of PPARγ inhibition on de novo lipid synthesis (Fig.  6b).

We considered it likely that the SNPs of interest could have a functional effect dependent on the differential allele binding of nuclear proteins.