Sentence examples for a functional domain from inspiring English sources

Protein-coding genes with ORF preserved could see their functionality significantly reduced if a deletion removes a functional domain.

The ORF ZBAI_02295 that contains a functional domain associated to the uncharacterised integral membrane proteins of unknown function of the DUP family is also suggested as a relevant tolerance determinant.

Defining a functional domain of PDCD10 is therefore important in learning how this protein functions and contributes to CCM development.

Proteins that regulate mRNA metabolism are often bipartite: an RNA binding activity confers substrate specificity, and a "functional" domain elicits the biological outcome.

Regulation of genes in vivo can be accomplished via the use of designed transcription factors — these result from a fusion of a designed DNA-binding domain based on the zinc finger protein motif to a functional domain of choice.

The objective of this work was to exploit the fibronectin type II (FNII) module from human matrix metalloproteinase-2 as a functional domain for the development of silk-based biopolymer blends that display enhanced cell adhesion properties.

Hutchins, 22, played a pivotal and unlikely role in stopping the spread of malware known as WannaCry when he discovered a functional domain kill switch for WannaCry.

This motif, that is in bacterial and fungal starch metabolizing enzymes, probably has been conserved during evolution as a functional domain for binding glycogen and starch.

The ssDNA contains a thiolated 5′-end, a regulatory domain of 12 adenine nucleotides, and a functional domain with absolute pairing with methylated p16 sequence (Met-p16).

The final ssDNA-GNP probe architecture contained a thiolated 5′-end, a regulatory domain of 12A nucleotides, and a functional domain with absolutely pairing match with Met-p16.

Here, we present computational results supported by experiments that the DR (RE3 and RE4) form a functional domain for recognition of a ComA dimer.