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Our results represent a significant functional demonstration of the existence of an algae ALS subunit and provide a solid basis for further studies on the structure, function and properties of ALS, as well as its response mechanism to inhibitors.
However, a functional demonstration was lacking, the time-course of activation was not investigated and an independent demonstration of gene expression was not available.
Buijs, R. M. et al. Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway.
With the functional demonstration of a role in erythrocyte invasion by Plasmodium falciparum parasites, implications in the aetiology of common conditions that prevail in individuals of African origin, and a wealth of pharmacological knowledge, the stimulatory G protein (Gs) signal transduction pathway presents an exciting target for anti-malarial drug intervention.
Our functional demonstration of a role for p15Ink4b in erythropoiesis and blood progenitor homeostasis provides a missing link in the regulation of such networks.
Gillies LA, Du H, Peters B, Knudson CM, Newmeyer DD, Kuwana T. Visual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes.
The first step in the creation of this reporter was the functional demonstration of the luciferase heterodimer formed by the luxAB genes [17].
The large fraction (65%) of ABCA4 mutations with allele frequencies of 1/400 or less (Fig. 4) limit the utility of allele specific testing methods and increase the dependence on patient derived cell lines for functional demonstration of their pathogenicity.
While full-immersion production systems are still rare, 3M partnered with Allied Control, Gigabyte, and PEZY to show functional demonstrations of 3M's Novec engineered fluids in the exhibition hall.
While combinatorial assessment of marker expression improves the robustness of molecular assays for pluripotency they ultimately remain surrogate assays, whereas functional demonstrations of cell potential provide more stringent tests of pluripotency.
It's not a fully functional demonstration by any stretch of the imagination, but T-Mobile has thrown together a browser-based G1 emulator and put it online for the sake of antsy tinkerers everywhere.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com