The phrase "a functional barrier" is correct and usable in written English.
It can be used to describe an obstacle or limitation that affects the functionality of a system, process, or interaction.
Example: "The lack of proper communication created a functional barrier between the departments, hindering collaboration."
Alternatives: "a practical obstacle" or "a usability constraint".
However, in maturing epithelia a tight junction complex and up-regulated transport features are leading to a functional barrier.
The existence of a functional barrier between the blood and lymph systems and the interior of the seminiferous tubule is well established [3], [4].
At the age of 10 days all tubular cells, in control (Figure 1A) as well as in SCARKO mice (Figure 1B), displayed hypertonicity-related shrinkage, indicating the absence of a functional barrier.
A switch to physiological (2 mM) calcium induces stratification and the formation of adherens and tight junctional complexes, but does not induce urothelial cytodifferentiation [14], although the cells retain the capacity to differentiate [15] and to form a functional barrier epithelium [16].
The vascular endothelium forms a functional barrier between the vessel wall and the bloodstream.
The tight junctions between Sertoli cells and between epididymis epithelial cells respectively, build a functional barrier of utmost competence [ 36].
A functional-barrier model was created with cultured RPE and human vascular cells separated by amniotic membrane (Hamilton and Leach, 2011).
A unique functional barrier to increase the shelf life of food products was discovered from gelatin based film formulated with lysozyme [7]. Figure 4 Antimicrobial activity of fish gelatin based films incorporated with a combination of catechin and lysozyme at different concentrations against S. cerevisiae, S. aureus, E. coli, and L. innocua.
Quantification of the fraction of tubules with a fully functional barrier (Figure S1) confirmed the differences in development between SCARKO and control testes but also showed that in SCARKO mice the fraction of tubules with an intact barrier increased from 18.2% at day 25 to 60.1% at day 35 and to 84.7% at adult age.
This organization provides a proper functional barrier to regulate vectorial secretion and intake of molecules.
The absence of enteric pathology in SHIP−/− hosts reconstituted with WT BM indicates that SHIP-deficiency does not cause an IEC functional barrier defect leading to ileitis.
