Sentence examples for a functional assignment from inspiring English sources

However, a large fraction of these newly discovered genes do not have a functional assignment.

However, using these probabilistic networks to produce a functional assignment remains a hard computational problem.

As revealed by the fact that the structural similarities of DS homologs were prone to be underestimated by conventional PSC methods (Fig. 2 and Figure S3), the proposed method may also serve as a functional assignment system for novel hypothetical proteins which escape typical sequence and structural similarity searches/detections.

Today, it is agreed that a functional assignment of the genome is needed [ 127].

K-means clustering was performed using Pearson correlation to split the selected features into five clusters from where features were chosen to conduct a functional assignment.

The 5.4 Mb genome contains approximately 5000 protein-coding genes, out of which ~70% have been given a functional assignment [ 18].

For newly displayed microbial genomes, about a third of the genes do not thus acquire any functional assignment.

Most of them (245) did not retrieve any functional assignment when probing the COG database.

In order to make a meaningful functional assignment to a protein family it is important to characterise the ancestral and derived motifs.

While we could see that protein domains from the same Pfam clan do indeed have similar DV I values, we were not able to show that domains that have either a low or a high DV I have a particular functional assignment, i.e. common GO annotations.

However, the lack of a relatively high sequence identity dismisses an accurate functional assignment and leads to a large number of cumulative homology-based misannotations, which can spread through functional databases (10).