Your English writing platform
Discover LudwigExact(4)
Both techniques have been previously applied to modelling transcript abundance as a function of transcriptional regulatory elements and demonstrated to yield comparable predictive performance [ 15– 15].
An obvious drawback of this approach is that integration is known to be non-random, but there is no model to account for this bias, and, especially, for possible variation in this bias as a function of transcriptional state of individual loci and physiological state of the cell.
In addition to copy number (discussed previously), robust levels of reporter gene expression are a function of transcriptional and translational signals.
To examine the effect of applying this lower threshold we plotted the fraction of genes within each constellation as a function of transcriptional territory sizes up to 200 kb (the estimated maximum distance between genes co-clustering as transcriptional territories [ 11]).
Similar(56)
These results suggest that the synergistic effect of IL-12 plus IL-18 treatment on IFN-γ expression is a function of both transcriptional and post-transcriptional effects.
Interestingly, no decrease in Hsp27 total RNA could be detected at any of the time points tested, indicating that LY30-mediated decrease in Hsp27 expression was not a function of its transcriptional regulation.
Nascent GILZ RNA expression in response to Dex and Dex + Gen treatment was examined to determine whether Gen antagonism of glucocorticoid-induced gene expression is a function of impeding transcriptional initiation (see Supplemental Material, Figure S2B).
G1 cyclin Cln1/2 is shown to modulate Ste20 activity of MAPK pathway for a function independent of transcriptional activation of FLO11 [43].
We have also measured the decay rate of the BG mRNAs by monitoring the declining concentration of each as a function of time after transcriptional arrest by a method described previously (Wu and Belasco, Methods in Enzymology, 2008).
Representative experiments measuring the amount of mCherry reporter mRNA in wild-type BY4741 (black) and upf1 Δ (blue) cells as a function of time following transcriptional shut-off for reporters containing (A ) (AAG 12, (B ) (AAA)12, and (C ) (AAG2AAA)4 inserts.
Our goal here is to give an introduction on the function of transcriptional factors, especially Bcl11b, in T cell development A most breakthrough advantage of using the mouse to study the immune system and to model human disease is the availability of a range of genetic technologies.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com