Abbreviations: BCS, breast conserving surgery; Nx, nodal status unknown; postmen., postmenopausal; RT, radiotherapy; PgR, progesterone receptor; pos., positive; neg., negative Figure 4 shows the estimated rate of recurrence as a function of PRO_10, PGR_5 and RISK_25 scores.
The lack of association with RFS may be a function of the difficulty of accurately coding of recurrence in a retrospective study that spanned such a long time period.
Second, because life expectancy is also a function of co-morbidity, performance states, and recurrence [ 23], the current estimates provide only a crude estimation of the average EYLL.
Kaplan-Meier estimates were generated for the proportion of patients free of distant recurrence as a function of time, and comparisons between groups were done using log-rank tests.
Here, we develop and fit a natural history model for the time to clinical tumour recurrence as a function of the number of involved lymph nodes, and derive plausible predictions of the effects of dose intensification under various conditions.
Cox proportional hazards regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of reduced overall and disease-free survival, death from breast cancer, and recurrence as a function of elevated plasma CRP levels.
We then plot tumor recurrence rates which are denoted as the red plot in the figure 2. The curve represents the tumor recurrence rates as a function of time (number of years after surgical removal of tumor).
39 Previously, WBRT combined with surgery plus chemowafers produced complete (100%) LC. 25 Because local recurrence rates are a function of both tumor volume and surgical technique, 40, 41 the extent to which local efficacy is attributable to advances in neurosurgical technology 40, 41 versus the effect of the carmustine wafer 42 cannot be determined without a controlled comparative trial.
The heuristic also can be extended to handle different costs for interaction addition and deletion by changing the constants in the recurrences to be a function of the parity of each flip.
Recurrence-free survival as a function of SOX4 expression is plotted in Figure 2B.
