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Within the ICF framework, activity limitations should, in part, be a function of diseases and disorders and their effects on bodily structures or function [ 7].
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Even without knowing the directionality of the changes, we can conclude that there is a dissociation between structural thalamo cortical brain changes in juvenile myoclonic epilepsy, along with aberrant functional thalamo cortical interactions that get worse as a function of disease severity as generalized tonic clonic seizures relate to more severe task-related dysfunction (Fig. 3A).
These factors are also discussed with respect to changes in mucus properties as a function of disease state.
Aggregation seems to increase as a function of disease severity [11], and early onset of migraine in the proband as well as the severity of migraines is associated with higher levels of family aggregation [14].
Furthermore, the expression of HDAC2 mRNA and protein in peripheral lung tissue and bronchoalveolar lavage macrophages, declined as a function of disease progression [9].
These findings suggest that despite the significant reduction in the proportion of tumor-reactive antibody cultures as a function of disease progression, patients from each of stage groups had B cells with antibodies that recognized tumor cells.
If it is possible to monitor changes in plasma AChE as a function of disease duration and progress, this may provide a new insight into the use of this enzyme as a diagnostic marker in the development of AD pathology.
The relative increase in each of these fucosylated glycan structures as a function of disease is shown in Figure 3B and shows that this structures changes in both liver cirrhosis and HCC.
These studies were focused on identifying differential regulation of genes during CS/CPB as a function of disease states, e.g. vascular permeability in patients with diabetes mellitus, or in association with clinical outcomes such as neurocognitive decline or atrial fibrillation.
Our findings alone do not describe why CFS or nPTLS occur, but are provided to illustrate that CSF proteome analysis may provide important and meaningful insights into the biological processes modulated as a function of disease and facilitate the identification of protein candidates for further investigation.
The results may simply be a function of disease severity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com