Sentence examples for a fully reconstituted from inspiring English sources

We further show in a fully reconstituted system that the interaction of p62 with ubiquitin and LC3B is sufficient to bend the membrane around the cargo.

Together, these data provide evidence that ribosome slipping on iterated AAA sequences occurs both in a fully reconstituted translation system and in E. coli.

To test these predictions, in vitro complementation studies were performed with the DSZS AT or KirCII added to a fully reconstituted DEBS assembly line in which the AT domain of the first module had been inactivated by site-directed mutagenesis.

Finally, it was also critical to test the ability of the SGSMs to modulate γ-secretase under conditions where the Aβ42/Aβ40 ratio was increased (i.e., cells overexpressing a mutant PS1), as well as the ability to modulate a highly purified γ-secretase enzyme complex in a fully reconstituted enzymatic assay.

Hopefully, a new and fully reconstituted legal system, one obtained through a bottom-up, participatory and inclusive institutional reform process, would allow Liberians to bring anyone who violates the law, including even those who are politically well connected, to justice.

A challenging step to further developing this model would be to connect the xenografted segments within the intestines of mice in order to establish a system that is fully reconstituted with normal microflora as well as the human or bovine immune systems.

In addition, PcG ubiquitin E3 ligase activity is enhanced within the molecular context of an intact PRC1 complex: fully reconstituted complexes containing RNF2, RING1, BMI1 and chromobox homolog 8 (CBX8) show highest activity compared to RNF2 alone or subcomplete PRC1 complexes [ 15].

We found that donor tissue from wt and RARα1/KO mice was able to repopulate the recipient glands; the highly branched ductal tree of the RARα1/KO donor was fully reconstituted in a wt-FVB recipient, indicating that the phenotype was epithelial cell autonomous.

We hypothesize that the Mn2+A site must be fully reconstituted with an additional histidine ligand to reintroduce significant metal binding activity, as designed in mutant MA2.

DOI: http://dx.doi.org/10.7554/eLife.03573.007 These highly purified pools of DKC1 RNPs were assayed over a threefold dose response range in our fully reconstituted in vitro transcription reactions containing OCT4, SOX2, recombinant XPC complex and SCC-B.

Nonetheless, we have changed the text to specify that our results are the first fully reconstituted in vitro demonstration of dynein-dependent sliding and have added a reference to the study that shows transport of stabilized seeds to the spindle pole by dynein (Heald et al., 1996).