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1900: Leonard Hill used a frog model to prove that decompression causes bubbles and that recompression resolves them.
The I152M mutation found in the study by Kirk et al. [ 41] also revealed increased actin expression in a frog model.
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For questions relating to a male frog's response to collisions with females, a "smart" frog model that changes its call composition in response to female proximity or female contact would be the design objective.
de Luna, Hödl, and Amézquita (2010) showed in a follow-up study that movement not only of the inflated vocal sac but also of a robotic frog model provoked territorial aggression in males of A. femoralis.
Linalool has acute local analgesic effects from low doses [ 49] in an in vitro frog model.
Fenchone has acute local analgesic effects [ 49] in an in vitro frog model.
For example, in X. tropicalis, a frog genetic model system, many of the exons have been identified, yet at least 5% of the genome, including exonic sequence, is in gaps in the latest genome assembly (v7.1) [ 18].
To assess the gene expression profiles in the frog model, we designed a novel multispecies frog cDNA microarray.
The safety of the formulations was tested by studying their effects on mucociliary transport rate (MTR) in a frog palate model and by measuring injury markers in rat bronchoalveolar fluid.
This could be characterised as the development of the radiopharmaceutical being 10 or even 20 years ahead of its ultimate realisation as a clinical tool, thus demonstrating that the leap frog model does not always apply.
Loosely connected limbs allowed the frog model (fabricated by David McCornack) to tremulate when coupled with an electronic shaker.
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