Loss of heterozigosity at the IGF2 gene has long been observed as a frequent occurrence in human breast cancer samples (McCann et al, 1996) and IGF-2 binding to IGF-1R and IR-A was found to facilitate activation of cell survival pathways (Richardson et al, 2011).
Perhaps — but profiling is a normal human occurrence.
In this work, we aimed to dissect the molecular mechanism of why bone metastasis is a frequent occurrence in the human disease but rare in mouse.
At places like Hurricane Ridge, where seeing humans is a frequent occurrence, most marmots will not acknowledge human presence at all.
For her it was a frequent enough occurrence to unlink Instagram from her Tinder.
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Most of this rain falls from thunderstorms, a frequent summer occurrence.
The temperatures of 30C (86F) and above this week have gone from being a very rare occurrence to, not a frequent occurrence, but much more likely," he said.
Genes containing multiple RRM domains were present in 28% of the RRM-containing human hits and this event is a frequent occurrence almost as a rule [ 9, 34].
We show that the abundance of bRG cells in the marmoset SVZ is similar to that in the developing gyrencephalic human and ferret neocortex, suggesting that a frequent occurrence of bRG cells, while perhaps necessary, is not sufficient, for gyrencephaly.
Officials said the guards' patience was often stretched, especially when inmates threw human waste at the military police officers, a frequent occurrence.
