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Among these seven missense mutations, six mutations were predicted by SIFT and PolyPhen 2 to have a deleterious effect on the protein function (Table S3), suggesting that there is a frequent disruption of the chromatin modification processes in the pathogenesis of ESCC.
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Obesity has been shown to increase the risk for obstructive sleep apnea syndrome, a disorder characterized by frequent disruption of breathing during sleep caused by closure of the airways [ 38- 40].
Enhancements in mass transfer of up to 30 fold were achieved by using a corrugated surface in place of a flat surface, due to the frequent disruption of the boundary layer imposed by the corrugated design.
Frequent disruption of circadian rhythm is an important tumor promoting factor.
Viral DNA integration leads to frequent disruption of the HPV-16 E2 gene (Kalantari et al, 1998), a negative regulator of the E6/ E7 promoter, resulting in the upregulation of the transcription of the E6 and E7 oncogenes.
There is frequent disruption at night, from alcoholics, drug users and people suffering from psychosis.
Lagos is not an easy city to live in, not just because of power cuts and the frequent disruption of other services, but because of the mentality this has engendered in the population.
The frequent disruption of the soil also releases the greenhouse gas carbon dioxide, he said, "so much of the benefit of growing Christmas trees in terms of absorbing greenhouse gases is undermined," he argued.
On the contrary, when the density is lower, vehicular networks show more similarity with DTNs, where the network is subject to more frequent disruption.
The first year of the statue's existence was a quiet one, while University College explored whether they could take legal action over it, but from November 1907 the students turned Battersea into the scene of frequent disruption.
The risk of bleeding in critically ill patients is high because of frequent disruption of the vascular wall and coagulopathy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com