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Finally, this work could serve as a foundation for discovery of the actions of miR-210, ISCU1/2, and Fe-S biology in additional diseases beyond PH that may share similar hypoxic, genetic, and metabolic underpinnings.
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The T.cruzi genome that was published in 2005 provided a foundation for discovery-based research of this human pathogen.
His work is also considered a foundation for the discovery of hepatitis viruses.
This approach, as well as the gene signature identified, provides important insights to the common metastatic process and a foundation for future discoveries that could have broad application, such as drug discovery, metastasis prediction, and mechanistic studies.
This data serves as a foundation for large-scale discovery of novel alleles for important rice phenotypes using various bioinformatics and/or genetic approaches.
In order to provide a foundation for education on e-discovery and security in Electronic Health Record (EHR) systems, this paper identifies emerging issues in the area.
Here we offer a foundation for the next decade of discovery!
With the reduction of sequencing cost brought by advanced generation sequencing approach, SNPs are becoming the first choice for construction of high-density genetic linkage map, in which the average marker interval can reach < 1 cM, thus providing more accurate foundation for discovery of functional genes and analysis of genome structure [ 48].
To enhance the foundation for discovery along these lines, we used high-throughput next-generation sequencing of total RNA (RNAseq) to profile RNA expression in the primary auditory cortex (A1) and medial geniculate body (MG) of mice at selected time-points during postnatal development, before and after the onset of hearing (postnatal days P7, P14, P21, and adult).
The publication of the annotated genome for S. Typhimurium LT2 provided a foundation for numerous applications, such as drug discovery [ 4].
Even though the massive amount of data obtained from a single experiment already prohibits the feasibility of manual data checking, we still found it necessary to perform such checks, at least for mass spectrometry based proteomics experiments where the goal of the study is to identify a reference data set as a foundation for future work, such as biomarker discovery.
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