Sentence examples for a forward screening from inspiring English sources

These results provide new evidence confirming that Tcf3 is a potent negative regulator of pluripotency and validate a forward screening methodology to identify modulators of pluripotent stem cell biology.

This protein subunit, which was identified as critical to hair cell function in a forward screening of hair cell dysfunction mutants in zebrafish, is normally present only in epithelial cells and not in other cell types including neurons (Ohno et al., 1999).

2) A strength of this work is that patronin was identified in a forward screen.

The mutant lines KK24, MM106 and M25 were previously identified by a forward screen of X-ray induced mutant lines [ 16, 17] of the soybean cultivar 'Bay' [ 18].

This is not very different from the spectrum of mutations observed in a forward screen in Drosophila, which were respectively 76, 6 and 10%% (the balance were deletions) [ 39], and is consistent with the mutational spectrum reported by TILLING of barley [ 36].

Despite Duffy's early discovery, it is not obvious that genetic mosaics would provide an effective forward screening method for this phenotype.

The second screen was a forward genetic screen for P element induced mutations that alter survival or development time of flies growing in 7% ethanol.

The Sleeping Beauty SBB) transposon system has proven useful for identifying drivers of tumorigenesis in a wide variety of tissue types [ 1], and it offers several advantages as a forward genetic screening tool.

Polley and Fay mention a forward genetic screen (from phenotype > gene) undertaken in previous work and describe a reverse genetic screen (from gene > phenotype) using RNAi.

We adopted a forward genetic screen strategy to uncover the Al-resistance mechanisms in rice.

To identify molecules involved in this process, we conducted a forward genetic screen in C. elegans and identified cima-1.