As they are not dissociable and their interaction is very significant, the optimisation of a formulation containing a mix of Gelucire cannot be done with polynomial models.
A formulation containing 12.4% w/w Kollidon® SR (K2 tablet) was found to be the most promising and stable for 6 months in an accelerated stability test.
It was found that a formulation containing 15% PEG can be created that produces a linear BT-release profile corresponding to BT eye drop delivery estimates.
The aim of this study was to develop a formulation containing fenofibrate and Gelucire® 50/13 (Gattefossé, France) in order to improve the oral bioavailability of the drug.
A formulation containing filler, glucose oxidase and electronic mediator was screen-printed over two carbon electrodes to form an integrated sensing/diffusion-limiting layer.
The effects of process conditions and the apparatus variables on the granulometric characteristics of a formulation containing a hydrophobic binder (stearic acid), lactose and paracetamol prepared by melt pelletization process were investigated in a 10-litre high shear mixer.
A 9-run design of experiments (DoE) that bracketed the range of commercially relevant mixer speeds, mixer orientations, and mass flow rates was executed using a formulation containing a cohesive drug substance at relatively low drug load.
A formulation containing 35.5% water, 2.5% gums, 4.7% proteins, 42.8% corn-starch, 10.7% corn flour, 1% NaCl, and 2.8% sunflower oil led to the highest values of G′, breaking force, and extensibility according to the optimization analysis performed.
Finally, a formulation containing Sorafenib retained its properties over a period of 90 days.
What is the effect of common extenders such as barium sulfate and calcium carbonate, introduced to a formulation containing photocatalytic TiO2, on the degradation rate?
