Sentence examples for a formidable obstacle to from inspiring English sources

His old club present a formidable obstacle to achieving it.

Together these provide a formidable obstacle to political change.Japanese society is consensual.

Domestic politics have proved to be a formidable obstacle to a resolution.

The vice-president, Dick Cheney, may anyway prove a formidable obstacle to implementing Bakerism.

If history is any measure, the Met can be a formidable obstacle to the redevelopment.

The scepticism of the German Chancellor had been a formidable obstacle to a comprehensive solution.

These data raise a potentially formidable obstacle to the delivery of clinically useful immunotherapies, suggesting that by the time a cancer becomes detectable it is already beyond the capabilities of the host immune system to eradicate it.

Of course, a formidable obstacle exists to any company dominating Broadway too grandly, and that has to do with seats.

It's the worst gringo hypocrisy!" Hypocrisy or not, Colombia's negative reputation can pose a formidable obstacle for locals attempting to lure American friends to visit.

Italy have won five of the last eight European Under-21 Championships but were beaten by Serbia on Monday, meaning that tomorrow's match represents a formidable obstacle as England seek to progress through Group B to the semi-finals.

The blood brain barrier (BBB) is a formidable obstacle preventing drug delivery to the brain, particularly for large protein therapeutics.