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A formal demonstration is provided by an experiment on instrumental conditioning discussed earlier.
A formal demonstration of this result could be obtained by studying the distribution of the residual nonlinearity (a uniform distribution is expected, but this shall be proved).
Suppliers of highly reliable and maintainable equipment are often well able to satisfy such conditions with little or no additional design or manufacturing effort, but incur difficulty and expense because a formal demonstration of these parameters may not have been previously attempted.
A formal demonstration that BI is inconsistent in the Felsenstein zone is beyond the scope of this paper.
Our analysis of cell shape and orientation, cell movements and the organization of the N-cadherin "3D adhesion basket" in s0 provide a formal demonstration that the caudal wall indeed epithelializes well before the rostral one (Figure 6A).
The findings provide a formal demonstration that in an endogamous and consanguineous population, calculated mtDNA genetic diversity is significantly lower using random sampling than using paternal or maternal household directed sampling.
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Since there are virtually no germ-line sequences corresponding to the tumor libraries in the EST database, there can not be any formal demonstration that the selected genes correspond to somatic mutation targets.
6 Formal demonstration of a direct clinical benefit arising from routine measurement of the pulse is challenging, owing to multiple potential biases and confounders, perhaps explaining why data addressing this question are scarce.
However, no formal demonstration of such a process has been published so far.
This would appear to be the first formal demonstration of such a (lack-of) relationship and is consistent with the literature reviews of Thomas and Hofer [ 40] and Pitches et al [ 9], although both reviews noted considerable and possibly confounding between-study heterogeneity in recorded process-of-care and mortality risk-adjustment measures.
However, the formal demonstration will still need a placebo-controlled randomised trial, which will be initiated in the Netherlands.
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