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A fold-back binding model was speculated in which the planar phenoxazone inserts at the GTC site with a loop-out T base whereas the G base at the 3′-terminus folds back to form a basepair with the internal C and stacks on the opposite face of the chromophore.
In plants, mature miRNAs are processed by the DICER-LIKE 1 (DCL1) RNase III-like protein from a longer nuclear-localized RNA transcript that forms a fold-back stem-loop structure of partially complementary double-stranded RNA (dsRNA).
The bilayered epithelial structure of the optic cup results from a fold-back movement that places the apices of the presumptive retina and RPE together.
Our search revealed an miR391 homolog, and a fold-back structure could be predicted for the precursor sequence in B. oleracea.
Small-85 is derived from the SRK gene that is capable of adopting a fold-back structure, and its expression is not dependent on RDR2 [ 32].
The remaining sequences were assigned as either other endogenous small RNAs or miRNA candidates and used for a fold-back structure prediction.
As subtelomeric DNA is histone (not Rap1p) associated, and Rap1p does not interact with histones, its detection in these regions is explained by a fold-back structure that puts the Rap1p-bound telomeric repeats in proximity to subtelomeric chromatin.
This chromatin structure is consistent with a fold-back model, previously proposed [ 17], in which the telomere physically interacts with the core X element, while the sequences in between loop-out and do not become involved in Sir-dependent silencing.
However, in terms of A to I editing of protein coding sequences, it is highly selective, and an imperfect fold back dsRNA structure is formed between the exon sequence surrounding the editing site(s) and a downstream intronic complementary sequence termed editing site complementary sequence.
He had opened the side of an oil drum like a book, folding back a leaf on either side.
In this model, a flap that can fold back on itself may be generated at the site of a nick and form an expansion precursor.
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