Sentence examples for a focused screening from inspiring English sources

Here, we describe a focused screening of adenosine derivatives using X-ray crystallography.

If the structure of the biological target is known a focused screening library could be designed, for example, through docking simulations.

First, the definition of the diagnosis can lead to a focused screening on its aetiology.

A focused screening library of ~2000 compounds was assembled from an in-house collection of previously synthesized kinase inhibitors utilizing a single concentration screening approach in a Nek2 biochemical kinase assay.

In a focused screening campaign, these 87 cell lines were monitored for differences in TLR signaling as measured by the release of the cytokine interleukin 6 (IL-6) into the supernatant after stimulation, a late quantitative read-out of TLR activation (Kawai and Akira, 2010).

Protein-ligand docking in BRD4(1) was used to purchase a small, focused screening set of compounds possessing a large variety of core structures.

The resulting overlays inspired a focused screen of 6-substituted azabenzimidazoles against TBK1/IKK-ε.

Indeed, a focused screen of pharmacological compounds that ameliorated the dnj-14 lifespan and neuronal defects identified the polyphenolic molecule resveratrol, which has been shown to be neuroprotective in a range of animal neurodegeneration models [71].

We undertook a focused screen of chemical compounds that exhibit protein aggregate-binding properties, such as Thioflavin T (ThT) and curcumin, widely used to stain these aggregates in post-mortem tissues of neurological disease affected individuals.

Specifically, we sought to provide a TB focused screening program for transport workers to measure uptake and the diagnostic yield of TB testing in a large transport center in central Johannesburg, South Africa.

Nevertheless, before recommending the adoption of a broader, more focused screening program of female soldiers, whether symptomatic or not, we recommend collecting additional data with a more randomized sampling strategy similar to that adopted by Gaydos et al. (4 ).