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'Inhalation by design' principles have been applied to a series of highly potent steroidal GR agonists, with a focus on optimising the potential therapeutic index in human.
12 13 In the Netherlands the setting of our study—an expert group with a focus on optimising extramural medication safety published specific recommendations for adequate GI protection, that is, prescribing PPIs in regular LDASA users with an increased risk of GI complications in 2008, which was finalised in 2009.
Training and education of general practitioners was defined as a professional intervention [ 21] that involves the use of guidelines or short training classes with a focus on optimising diagnosis as well as treatment.
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In line with a recent focus on optimising knowledge translation, effective dissemination and impact is a critical component of all research.
Together, these findings argue for the importance of promoting targeted lifestyle and exercise interventions that focus on improving muscle strength, balance and gait in older adults, with a particular focus on optimising muscle strength from the age of 50 years and balance and gait speed from 60 years and older.
A medium term outcome of this intervention would focus on optimising lifestyle beyond the perinatal period for example collaborating with health visiting services to provide education and support that would potentially have a longer term outcome of improved family health and well being.
In the current literature on morphological implementation, authors focus on optimising the pipeline delay process for a latency efficient morphology operator implementation [25, 27 31], while recent notable contributions by Bartovsky et al. instead proposed optimising the entire morphological filter operator chain [32].
Our own investigations will focus on optimising the current compounds for binding to hDM2 and targeting other PPIs.
Future efforts should focus on optimising the GPs' awareness of the need to elicit and manage expectations and develop skills in integrating shared decision making into the consultation.
A number of recommendations have been made to address the issues surrounding the return of genetic results described above and primarily focus on optimising the informed consent process and developing mechanisms for feedback of results to research participants.
5 In recent years there has been increasing focus on optimising women's nutrition and lifestyle in the periconceptional period, as this is a key time for fetal development.
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