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The test consisted of poking a hind paw to provoke a flexion reflex followed by a clear flinch response after paw withdrawal.
The acoustic startle response is characterised by an exaggerated flinching response to an unexpected auditory stimulus.
To determine whether the effects of IT BoNT-B on primary afferents fibers at doses which block neurotransmitter release and C-Fos activation alter nocifensive behavior, the effects of IT BoNT-B on formalin-induced flinching response was examined.
Mice that received IT BoNT-B 0.5 U 2-day pretreatment showed significant reduction in phase II, but not phase I, of formalin-evoked flinching response, as compared to vehicle animals (figure 6A).
IT BoNTB, at doses having no effect upon motor function produced persistent (as long as 30 days) and significant effects upon the phase 2 of the formalin-induced flinching response and reversed the tactile allodynia otherwise occurring after nerve injury for at least 15 days.
Probit analysis with 95% confidence intervals was used to test for significant differences in flinching response between genotypes to increasing shock intensity.
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J.G.: I think the Arabs saw that as a flinch.
In a flinch they are gone.
I feel a flinch of annoyance.
His biggest strength is never flinching, writes Mark Kriegel on Foxsports.com, no matter how much the situation calls for a flinch.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com