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A fixed single dose of adoptively transferred FAP-specific re-directed T cells will be given in the pleural effusion.
The primary objective is to test safety of a fixed single dose of adoptively transferred FAP-specific re-directed T cells in the pleural effusion.
This is a phase I trial for patients with malignant pleural mesothelioma with pleural effusion testing the safety of a fixed single dose of 1x10 adoptively transferred FAP-specific re-directed T cells given directly in the pleural effusion.
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32 The efficacy and safety of a fixed, single intravenous dose of palonosetron in preventing CINV have been assessed in five phase I, one phase II, and three phase III trials.
For PK studies, the mice were killed at fixed time points after a single dose of 100 mg kg−1 IP dFdC, and plasma and tumour were then snap-frozen.
IVF allows breeders to fertilize more than a hundred eggs with a single dose of semen.
Included studies had to use either a single dose of BTX-A to treat TN, or investigate different dosing strategies.
The pilot study (part 1) had a fixed-sequence design (multiple doses of dabigatran 150 mg followed by a single dose of clopidogrel) for safety reasons.
Each animal only received a single dose of a NSAID.
A single dose of an amphetamine increases wakefulness and alertness as well as initiative, self-confidence, concentration and sustained attention.
HOPE-4 seeks to design and evaluate an intervention that will comprise fixed single pill fixed dose cardiovascular combination therapy, coupled with advice on self-management, administered by mid-level non physician health workers.
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