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For all 5 species models of the 17β-HSD 1 enzymes the consensus method predicted estrone (compound 6) as the most potent inhibitor (best fitting compound) in agreement with the experimental data (Figure 4 and Table 2).
The compounds displaying high docking score were visually prioritized to identify the best-fitting compounds, i. e. the ones which adequately mimic the interactions of clinical candidate inhibitor Nutlin-3a.
It is a fitting description.
"This was a fitting tribute".
It's a fitting end.
A fitting epitaph.
"This is a fitting tribute".
It's a fitting revenge.
No, but a fitting one.
A fitting end.
A fitting way to go out, too.
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CEO of Professional Science Editing for Scientists @ prosciediting.com