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The phrase "a first portion of" is correct and usable in written English.
It can be used when referring to an initial segment or part of something, often in a context where multiple portions or segments are being discussed.
Example: "In this report, we will analyze a first portion of the data collected during the survey."
Alternatives: "an initial part of" or "a preliminary segment of".
Exact(1)
A first portion of dexamethasone appeared shortly after the injection, indicating a small fraction of free DXM-P or drug associated with the outer layer of the liposomes.
Similar(59)
We just order a second portion of the spare ribs, and reminisce about the Cantonese restaurants of our childhood.
A second portion of my summer will be solely dedicated to thesis work in Johannesburg and Bloemfontein.
If he is found guilty, a second portion of the trial would determine if he will be sentenced to death.
A second portion of the cremated remains of Gene Roddenberry, creator of "Star Trek," is scheduled for a trip into the great unknown together with those of his wife, Majel Barrett Roddenberry, The Associated Press reported.
A second portion of the trial, Master 2, will compare the T-wave's performance as a predictor of seizures in patients who did not get defibrillators with the group that did get the implants.
A second portion of the process involves repacking — essentially moving and squeezing together the remaining airwaves so they occupy a smaller portion of the spectrum band, known as UHF.
This week, Mr. Papandreou is struggling to persuade his increasingly disruptive party members that Greece must agree to another round of austerity measures to qualify for a second portion of loans from the European Union and the International Monetary Fund.
Four minutes later, a second portion of the mountain fell after losing support from below.
Concentrated trace metal grade HNO3 is added to preserve a second portion of each sample for trace metal analyses using ICP-MS.
In a second portion of the call, the voice of a person identifying himself as a physician said, "No other weapons," presumably in response to a dispatcher query.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com