Sentence examples for a first necessity from inspiring English sources

Despite unclear upstream mechanisms, NLRP3 is expressed at limiting levels in macrophages or dendritic cells, possibly to avoid unintended inflammation, and requires a PRR-dependent priming signal via TLRs as a first necessity for its subsequent activation (Bauernfeind et al, 2009; Juliana et al, 2012).

A second necessity is to give interest rate relief on sovereign debt, to lessen the ramifications of the excessive debt in the financial system.

The first necessity is a development of a guideline for economic evaluations.

The first necessity for a blank slate is an omnipotent eraser, and the guillotine was the one at hand.

Whether the structure is a single-family house or a thirty-story building, the first necessity is that every room have light and air.

The first necessity is a reform of the Greek economic structure.

A visit to the camp barber was the first necessity for the recruits, where a close "number one" cut was the only style on offer.

The first necessity was to establish a legitimate basis of action.

The first necessity for organizational health is building a cohesive leadership team.

The first necessity for Mrs. Clinton — high turnout — is a virtual certainty.

High ceilings were the first necessity but plenty of other smaller trivial things needed a reworking, too.